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Vortioxetine and Cognitive Function: A Promising Connection

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  • Vortioxetine and Cognitive Function: A Promising Connection
Vortioxetine and Cognitive Function: A Promising Connection
  • Jun, 1 2023
  • Posted by Cillian Osterfield
Cillian Osterfield
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Cillian Osterfield

5 comments

Don Moore

Don Moore

Vortioxetine's impact on cognitive function is one of the more compelling developments in psychiatric pharmacology in the last decade. The multimodal mechanism-serotonin reuptake inhibition combined with receptor modulation-offers a nuanced approach that SSRIs simply can't match. Clinical trials consistently show improvements in processing speed and executive function, particularly in patients with residual cognitive deficits after depressive episodes. This isn't just about mood stabilization; it's about restoring cognitive integrity.

Mathias Matengu Mabuta

Mathias Matengu Mabuta

You're all ignoring the elephant in the room. Vortioxetine is just another pharmaceutical profit engine disguised as a cognitive enhancer. The FDA approved it based on surrogate endpoints-nothing clinically meaningful. The trials were funded by Lundbeck. The ‘cognitive improvements’? Statistically significant but clinically negligible. And don’t get me started on the side effect profile: nausea, sexual dysfunction, and now they’re telling us it ‘enhances cognition’? Please.

Ikenga Uzoamaka

Ikenga Uzoamaka

I've been on this drug for 8 months... and I can finally finish a book!!! I used to read one page and forget what it was about... now I remember names, dates, even the damn plot twists!!! I'm not crying, you're crying!!!

Lee Lee

Lee Lee

They’re not telling you the truth. Vortioxetine was developed as part of a broader neurocontrol initiative. The cognitive improvements? A side effect of subtly rewiring default mode network activity to increase compliance. The real goal is behavioral predictability. Look at the patent filings-there’s a hidden algorithm embedded in the molecular structure. It’s not medicine. It’s social engineering. And yes, I’ve read the original clinical trial data. The numbers don’t lie. They’re just hiding in plain sight.

John Greenfield

John Greenfield

Ikenga Uzoamaka’s comment is the only honest one here. I’ve been on vortioxetine for a year. My brain doesn’t feel ‘enhanced’-it feels like it’s running on a slow processor with too many background apps. But I can focus long enough to pay my bills. So maybe it’s not magic. Maybe it’s just… less terrible than the alternatives. Still, I’d rather have a good therapist and a decent sleep schedule.

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